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Fuji Photo Film (Europe) GmbH and the bio-technology company Molzym in Bremen signed an agreement on the common development of an automatic preparation of samples for the diagnosis of sepsis. The core piece of the automatization is the QuickGene-810 system for automatic isolation of nucleic acids which Fujifilm introduced in April 2005. In connection with the pre-analysis kit "MolYsis" by Molzym this will result in a fast, efficient and cost-favourable system for the preparation of test specimens for the PCR-based diagnosis of sepsis. A prototype of the automatized process is presently being tested within the frame of a clinical study. 

 

Blood poisoning, also called sepsis, are serious infectious diseases. According to a recently published study more people die from sepsis than from acute myocardial infarction. Despite of intensive research there has not been any success in considerably declining the high mortality rates.

Especially the detection of the pathogenic organism is of central importance for the therapy. This is done in hospitals or laboratory practices by means of diagnosis of blood cultures. Although theses processes have been standardized, they sometimes take several days; furthermore these processes are not always reliable, for example in cases when a therapy with antibiotics has already been started.

On the contrary molecular analysis (PCR and chip-based technologies) has the considerable advantage of a timely diagnosis of sepsis. The result which the treating doctor needs is available at a much earlier point of time, i.e. sometimes even after four to six hours. Even in cases when a therapy with antibiotics has already been started, the results are reliable.

"With MolYsis we have developed a completely new approach for the solution of the large number of problems of molecular analysis. Instead of removing every error individually we exclude the sources of errors by using pre-analysis form the very beginnig", says Professor Dr Michael Lorenz, CEO of Molzym. For this purpose the process is presently being automatized together with Fujifilm.

"The automatization features the advantage of a possibly higher throughput of samples with simultaneous reduction of the necessary workforce", says Dr Michael Kaling, European Manager Life Science at Fujifilm. The MolYsis technology in combination with the QuickGene-810 has already been used in numerous companies as a platform for the development of molecular-biological procedures of diagnosis.

Düsseldorf, March 9th, 2005

 

Further information:
http://www.fujifilm.de/lifescience.html
http://lifescience.fujifilm.com
http://www.molzym.com

PDF iconsee PDF for more info (in German) »

PDF iconEnglish translation » 

 

We are proud to announce that we as of October 1st are the official distributor of Biospace Lab in Scandinavia as well as in Finland.

Biospace offers novel instruments for real-time imaging of small animals in vivo that open possibilities in pharmacokinetics and functional imaging that greatly accelerate development times.

 

 

www.biospace.fr

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